As of 2020, the Minneapolis–St. Paul area is the second-largest economic center in the American Midwest behind Chicago.[127] Early the city's history, millers were required to pay for wheat with cash during the growing season, and then to store the wheat until it was needed for flour. This required large amounts of capital, which stimulated the local banking industry and made Minneapolis a major financial center.[128] As of mid-2022, Minneapolis area employment is primarily in trade, transportation, utilities, education, health services, professional and business services. Smaller numbers are employed in manufacturing, leisure and hospitality; mining, logging, and construction.[129] The Twin Cities metropolitan area has the seventh-highest concentration of major corporate headquarters in the US as of 2021,[130] and in 2020, four Fortune 500 corporations were headquartered within the city limits of Minneapolis.[131] American companies with US offices in Minneapolis include Accenture, Bellisio Foods,[132] Canadian Pacific, Coloplast,[133] RBC[134] and Voya Financial.[135] The National Institute for Pharmaceutical Technology & Education has Minneapolis headquarters. As of 2020, the Minneapolis metropolitan area contributes $273 billion or 74% to the gross state product of Minnesota.[136] Measured by gross metropolitan product per resident ($62,054), as of 2015, Minneapolis is the fifteenth richest city in the US.[137] In 2011, the area's $199.6 billion gross metropolitan product and its per capita personal income ranked 13th in the US.[138] The Minneapolis Grain Exchange, which w
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